Meckel’s and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible
Activating FGFR3 mutations in human result in achondroplasia (ACH), the most frequent form of dwarfism, where cartilages are severely disturbed causing long bones, cranial base and vertebrae defects. Because mandibular development and growth rely on cartilages that guide or directly participate to t...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181594/ https://www.ncbi.nlm.nih.gov/pubmed/27260401 http://dx.doi.org/10.1093/hmg/ddw153 |