MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex

Rett syndrome (RTT; OMIM 312750), a progressive neurological disorder, is caused by mutations in methyl-CpG-binding protein 2 (MECP2; OMIM 300005), a ubiquitously expressed factor. A genetic suppressor screen designed to identify therapeutic targets surprisingly revealed that downregulation of the c...

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Detalles Bibliográficos
Autores principales: Kyle, Stephanie M., Saha, Pradip K., Brown, Hannah M., Chan, Lawrence C., Justice, Monica J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181597/
https://www.ncbi.nlm.nih.gov/pubmed/27288453
http://dx.doi.org/10.1093/hmg/ddw156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181597/
https://www.ncbi.nlm.nih.gov/pubmed/27288453
http://dx.doi.org/10.1093/hmg/ddw156

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