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MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex
Rett syndrome (RTT; OMIM 312750), a progressive neurological disorder, is caused by mutations in methyl-CpG-binding protein 2 (MECP2; OMIM 300005), a ubiquitously expressed factor. A genetic suppressor screen designed to identify therapeutic targets surprisingly revealed that downregulation of the c...
Autores principales: | Kyle, Stephanie M., Saha, Pradip K., Brown, Hannah M., Chan, Lawrence C., Justice, Monica J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181597/ https://www.ncbi.nlm.nih.gov/pubmed/27288453 http://dx.doi.org/10.1093/hmg/ddw156 |
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