Early hypermethylation of hepatic Igfbp2 results in its reduced expression preceding fatty liver in mice

Obesity and ectopic fat disposition are risk factors for metabolic disease. Recent data indicate that IGFBP2 expression in liver is epigenetically inhibited during hepatic steatosis. The aim of this study was to investigate if epigenetic de-regulation of hepatic Igfbp2 occurs already early in life a...

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Detalles Bibliográficos
Autores principales: Kammel, Anne, Saussenthaler, Sophie, Jähnert, Markus, Jonas, Wenke, Stirm, Laura, Hoeflich, Andreas, Staiger, Harald, Fritsche, Andreas, Häring, Hans-Ulrich, Joost, Hans-Georg, Schürmann, Annette, Schwenk, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181631/
https://www.ncbi.nlm.nih.gov/pubmed/27126637
http://dx.doi.org/10.1093/hmg/ddw121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181631/
https://www.ncbi.nlm.nih.gov/pubmed/27126637
http://dx.doi.org/10.1093/hmg/ddw121

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