Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson’s disease

Mutations in GBA1, the gene encoding glucocerebrosidase, are associated with an enhanced risk of developing synucleinopathies such as Parkinson’s disease (PD) and dementia with Lewy bodies. A higher prevalence and increased severity of motor and non-motor symptoms is observed in PD patients harborin...

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Detalles Bibliográficos
Autores principales: Rockenstein, Edward, Clarke, Jennifer, Viel, Catherine, Panarello, Nicholas, Treleaven, Christopher M., Kim, Changyoun, Spencer, Brian, Adame, Anthony, Park, Hyejung, Dodge, James C., Cheng, Seng H., Shihabuddin, Lamya S., Masliah, E., Sardi, S. Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181635/
https://www.ncbi.nlm.nih.gov/pubmed/27126635
http://dx.doi.org/10.1093/hmg/ddw124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181635/
https://www.ncbi.nlm.nih.gov/pubmed/27126635
http://dx.doi.org/10.1093/hmg/ddw124

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