Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects

Mutations in β-catenin (CTNNB1) have been implicated in cancer and mental disorders. Recently, loss-of-function mutations of CTNNB1 were linked to intellectual disability (ID), and rare mutations were identified in patients with autism spectrum disorder (ASD). As a key regulator of the canonical Wnt...

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Detalles Bibliográficos
Autores principales: Dong, Fengping, Jiang, Joanna, McSweeney, Colleen, Zou, Donghua, Liu, Long, Mao, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181638/
https://www.ncbi.nlm.nih.gov/pubmed/27131348
http://dx.doi.org/10.1093/hmg/ddw131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181638/
https://www.ncbi.nlm.nih.gov/pubmed/27131348
http://dx.doi.org/10.1093/hmg/ddw131

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