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Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes

Alteration of mitochondria-associated membranes (MAMs) has been proposed to contribute to the pathogenesis of Alzheimer’s disease (AD). We studied herein the subcellular distribution, the processing, and the protein interactome of the amyloid-β protein precursor (AβPP) and its proteolytic products i...

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Detalles Bibliográficos
Autores principales: Del Prete, Dolores, Suski, Jan M., Oulès, Bénédicte, Debayle, Delphine, Gay, Anne Sophie, Lacas-Gervais, Sandra, Bussiere, Renaud, Bauer, Charlotte, Pinton, Paolo, Paterlini-Bréchot, Patrizia, Wieckowski, Mariusz R., Checler, Frédéric, Chami, Mounia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181669/
https://www.ncbi.nlm.nih.gov/pubmed/27911326
http://dx.doi.org/10.3233/JAD-160953