25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation

Lassa virus (LASV) infection is a major public health concern due to high fatality rates and limited effective treatment. The interferon-stimulated gene cholesterol 25-hydroxylase (CH25H) encodes an enzyme that catalyzes the production of 25-hydroxycholesterol (25HC). 25HC is involved in regulating...

Descripción completa

Detalles Bibliográficos
Autores principales: Shrivastava-Ranjan, Punya, Bergeron, Éric, Chakrabarti, Ayan K., Albariño, César G., Flint, Mike, Nichol, Stuart T., Spiropoulou, Christina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181775/
https://www.ncbi.nlm.nih.gov/pubmed/27999160
http://dx.doi.org/10.1128/mBio.01808-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181775/
https://www.ncbi.nlm.nih.gov/pubmed/27999160
http://dx.doi.org/10.1128/mBio.01808-16

Ejemplares similares