OH cleavage from tyrosine: debunking a myth

During macromolecular X-ray crystallography experiments, protein crystals held at 100 K have been widely reported to exhibit reproducible bond scission events at doses on the order of several MGy. With the objective to mitigate the impact of radiation damage events on valid structure determination,...

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Detalles Bibliográficos
Autores principales: Bury, Charles S., Carmichael, Ian, Garman, Elspeth F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182017/
https://www.ncbi.nlm.nih.gov/pubmed/28009542
http://dx.doi.org/10.1107/S1600577516016775