Conformational variation of proteins at room temperature is not dominated by radiation damage

Protein crystallography data collection at synchrotrons is routinely carried out at cryogenic temperatures to mitigate radiation damage. Although damage still takes place at 100 K and below, the immobilization of free radicals increases the lifetime of the crystals by approximately 100-fold. Recent...

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Detalles Bibliográficos
Autores principales: Russi, Silvia, González, Ana, Kenner, Lillian R., Keedy, Daniel A., Fraser, James S., van den Bedem, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Radiation Damage
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182021/
https://www.ncbi.nlm.nih.gov/pubmed/28009548
http://dx.doi.org/10.1107/S1600577516017343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182021/
https://www.ncbi.nlm.nih.gov/pubmed/28009548
http://dx.doi.org/10.1107/S1600577516017343

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