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Sustained Contraction in Vascular Smooth Muscle by Activation of L-type Ca(2+) Channels Does Not Involve Ca(2+) Sensitization or Caldesmon

Vascular smooth muscle (VSM) is unique in its ability to maintain an intrinsic level of contractile force, known as tone. Vascular tone is believed to arise from the constitutive activity of membrane-bound L-type Ca(2+) channels (LTCC). This study used a pharmacological agonist of LTCC, Bay K8644, t...

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Detalles Bibliográficos
Autores principales: Ets, Hillevi K., Seow, Chun Y., Moreland, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183594/
https://www.ncbi.nlm.nih.gov/pubmed/28082901
http://dx.doi.org/10.3389/fphar.2016.00516