Imiquimod Treatment Causes Systemic Disease in Mice Resembling Generalized Pustular Psoriasis in an IL-1 and IL-36 Dependent Manner

Generalized pustular psoriasis (GPP) is a severe form of psoriasis that can be caused by missense mutations in the interleukin-36 (IL-36) receptor antagonist. In addition to neutrophil rich skin inflammation, GPP patients typically also experience anorexia, fever, malaise, and pain. The imiquimod-in...

Descripción completa

Detalles Bibliográficos
Autores principales: Alvarez, Pilar, Jensen, Liselotte E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183767/
https://www.ncbi.nlm.nih.gov/pubmed/28057979
http://dx.doi.org/10.1155/2016/6756138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183767/
https://www.ncbi.nlm.nih.gov/pubmed/28057979
http://dx.doi.org/10.1155/2016/6756138

Ejemplares similares