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CLOCK Promotes Endothelial Damage by Inducing Autophagy through Reactive Oxygen Species

A number of recent studies have implicated that autophagy was activated by reactive oxygen species (ROS). Our previous report indicated that CLOCK increased the accumulation of ROS under hypoxic conditions. In this study, we investigated the mechanisms by which CLOCK mediated endothelial damage, foc...

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Detalles Bibliográficos
Autores principales: Tang, Xiao, Lin, Changpo, Guo, Daqiao, Qian, Ruizhe, Li, Xiaobo, Shi, Zhenyu, Liu, Jianjun, Li, Xu, Fan, Longhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183792/
https://www.ncbi.nlm.nih.gov/pubmed/28058089
http://dx.doi.org/10.1155/2016/9591482