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Dihydropyrimidine dehydrogenase mutation in neoadjuvant chemotherapy in head and neck cancers: Myth or reality?

PURPOSE: The docetaxel, 5-fluorouracil (5-FU), and cisplatin (TPF) regimen in India is associated with high percentages of Grade 3–4 toxicity. This analysis was planned to evaluate the incidence of dihydropyrimidine dehydrogenase (DPD) mutation in patients with severe gastrointestinal toxicity, to a...

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Detalles Bibliográficos
Autores principales: Patil, Vijay M., Noronha, Vanita, Joshi, Amit, Zanwar, Saurabh, Ramaswamy, Anant, Arya, Supreeta, Mahajan, Abhishek, Bhattacharjee, Atanu, Prabhash, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5184753/
https://www.ncbi.nlm.nih.gov/pubmed/28032083
http://dx.doi.org/10.4103/2278-330X.195338