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Dihydropyrimidine dehydrogenase mutation in neoadjuvant chemotherapy in head and neck cancers: Myth or reality?
PURPOSE: The docetaxel, 5-fluorouracil (5-FU), and cisplatin (TPF) regimen in India is associated with high percentages of Grade 3–4 toxicity. This analysis was planned to evaluate the incidence of dihydropyrimidine dehydrogenase (DPD) mutation in patients with severe gastrointestinal toxicity, to a...
Autores principales: | Patil, Vijay M., Noronha, Vanita, Joshi, Amit, Zanwar, Saurabh, Ramaswamy, Anant, Arya, Supreeta, Mahajan, Abhishek, Bhattacharjee, Atanu, Prabhash, Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5184753/ https://www.ncbi.nlm.nih.gov/pubmed/28032083 http://dx.doi.org/10.4103/2278-330X.195338 |
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