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Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker Studies
TGF-β induces complicated and even opposite responses in numerous biological processes, e.g., tumor suppression in pre-malignant cells and metastasis promotion in cancer cells. However, the cellular contextual determinants of these different TGF-β roles remain elusive, and the driver genes triggerin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5184782/ https://www.ncbi.nlm.nih.gov/pubmed/27916872 http://dx.doi.org/10.3390/jcm5120109 |