Electrophysiological Characteristics of the LQT2 Syndrome Mutation KCNH2-G572S and Regulation by Accessory Protein KCNE2

Mutations in hERG cause long QT syndrome type 2 which is characterized by a prolonged QT interval on electrocardiogram and predisposition to life-threatening ventricular tachyarrhythmia, syncope, and sudden death. hERG-G572S induces trafficking defects of hERG channel protein from Golgi to the plasm...

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Detalles Bibliográficos
Autores principales: Liu, Li, Tian, Jinwen, Lu, Caiyi, Chen, Xi, Fu, Yicheng, Xu, Bin, Zhu, Chao, Sun, Yanmei, Zhang, Yu, Zhao, Ying, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187237/
https://www.ncbi.nlm.nih.gov/pubmed/28082916
http://dx.doi.org/10.3389/fphys.2016.00650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187237/
https://www.ncbi.nlm.nih.gov/pubmed/28082916
http://dx.doi.org/10.3389/fphys.2016.00650

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