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Electrophysiological Characteristics of the LQT2 Syndrome Mutation KCNH2-G572S and Regulation by Accessory Protein KCNE2

Mutations in hERG cause long QT syndrome type 2 which is characterized by a prolonged QT interval on electrocardiogram and predisposition to life-threatening ventricular tachyarrhythmia, syncope, and sudden death. hERG-G572S induces trafficking defects of hERG channel protein from Golgi to the plasm...

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Detalles Bibliográficos
Autores principales:	Liu, Li, Tian, Jinwen, Lu, Caiyi, Chen, Xi, Fu, Yicheng, Xu, Bin, Zhu, Chao, Sun, Yanmei, Zhang, Yu, Zhao, Ying, Li, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187237/ https://www.ncbi.nlm.nih.gov/pubmed/28082916 http://dx.doi.org/10.3389/fphys.2016.00650

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