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The Importance of an In-depth Study of Immunoglobulin Gene Rearrangements When Ascertaining the Clonal Relationship between Concomitant Chronic Lymphocytic Leukemia and Multiple Myeloma

Chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) are hematological disorders that occur at different stages of B-cell development. It has been shown that CLL B-cells can differentiate into plasma cells in vitro and in vivo. CLL is the most frequent adult leukemia in the western world. It...

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Detalles Bibliográficos
Autores principales: Trudel, Stéphanie, Ghamlouch, Hussein, Dremaux, Julie, Delette, Caroline, Harrivel, Véronique, Marolleau, Jean-Pierre, Gubler, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187371/
https://www.ncbi.nlm.nih.gov/pubmed/28082975
http://dx.doi.org/10.3389/fimmu.2016.00625