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The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins

Mitochondrial protein import is essential for all eukaryotes. Here we show that the early diverging eukaryote Trypanosoma brucei has a non-canonical inner membrane (IM) protein translocation machinery. Besides TbTim17, the single member of the Tim17/22/23 family in trypanosomes, the presequence tran...

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Detalles Bibliográficos
Autores principales: Harsman, Anke, Oeljeklaus, Silke, Wenger, Christoph, Huot, Jonathan L., Warscheid, Bettina, Schneider, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187411/
https://www.ncbi.nlm.nih.gov/pubmed/27991487
http://dx.doi.org/10.1038/ncomms13707