Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies

Active targeting of nanoparticles to tumours can be achieved by conjugation with specific antibodies. Specific active targeting of the HER2 receptor is demonstrated in vitro and in vivo with a subcutaneous MCF-7 breast cancer mouse model with trastuzumab-functionalized gold nanoparticles. The number...

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Detalles Bibliográficos
Autores principales: Colombo, Miriam, Fiandra, Luisa, Alessio, Giulia, Mazzucchelli, Serena, Nebuloni, Manuela, De Palma, Clara, Kantner, Karsten, Pelaz, Beatriz, Rotem, Rany, Corsi, Fabio, Parak, Wolfgang J., Prosperi, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187442/
https://www.ncbi.nlm.nih.gov/pubmed/27991503
http://dx.doi.org/10.1038/ncomms13818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187442/
https://www.ncbi.nlm.nih.gov/pubmed/27991503
http://dx.doi.org/10.1038/ncomms13818

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