Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

Comprehensive knowledge of immunoglobulin genetics is required to advance our understanding of B cell biology. Validated immunoglobulin variable (V) gene databases are close to completion only for human and mouse. We present a novel computational approach, IgDiscover, that identifies germline V gene...

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Detalles Bibliográficos
Autores principales: Corcoran, Martin M., Phad, Ganesh E., Bernat, Néstor Vázquez, Stahl-Hennig, Christiane, Sumida, Noriyuki, Persson, Mats A.A., Martin, Marcel, Hedestam, Gunilla B. Karlsson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187446/
https://www.ncbi.nlm.nih.gov/pubmed/27995928
http://dx.doi.org/10.1038/ncomms13642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187446/
https://www.ncbi.nlm.nih.gov/pubmed/27995928
http://dx.doi.org/10.1038/ncomms13642

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