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Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

Comprehensive knowledge of immunoglobulin genetics is required to advance our understanding of B cell biology. Validated immunoglobulin variable (V) gene databases are close to completion only for human and mouse. We present a novel computational approach, IgDiscover, that identifies germline V gene...

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Detalles Bibliográficos
Autores principales:	Corcoran, Martin M., Phad, Ganesh E., Bernat, Néstor Vázquez, Stahl-Hennig, Christiane, Sumida, Noriyuki, Persson, Mats A.A., Martin, Marcel, Hedestam, Gunilla B. Karlsson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187446/ https://www.ncbi.nlm.nih.gov/pubmed/27995928 http://dx.doi.org/10.1038/ncomms13642

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