Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations

ATP-binding cassette transporter G2 (ABCG2) is a plasma membrane protein that regulates the pharmacokinetics of a variety of drugs and serum uric acid (SUA) levels in humans. Despite the pharmacological and physiological importance of this transporter, there is no clinically available drug that modu...

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Detalles Bibliográficos
Autores principales: Miyata, Hiroshi, Takada, Tappei, Toyoda, Yu, Matsuo, Hirotaka, Ichida, Kimiyoshi, Suzuki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187494/
https://www.ncbi.nlm.nih.gov/pubmed/28082903
http://dx.doi.org/10.3389/fphar.2016.00518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187494/
https://www.ncbi.nlm.nih.gov/pubmed/28082903
http://dx.doi.org/10.3389/fphar.2016.00518

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