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A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity

Alzheimer's disease (AD) researchers commonly use MRI as a quantitative measure of disease severity. Historically, hippocampal volume has been favored. Recently, “AD signature” measurements of gray matter (GM) volumes or cortical thicknesses have gained attention. Here, we systematically evalua...

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Detalles Bibliográficos
Autores principales: Schwarz, Christopher G., Gunter, Jeffrey L., Wiste, Heather J., Przybelski, Scott A., Weigand, Stephen D., Ward, Chadwick P., Senjem, Matthew L., Vemuri, Prashanthi, Murray, Melissa E., Dickson, Dennis W., Parisi, Joseph E., Kantarci, Kejal, Weiner, Michael W., Petersen, Ronald C., Jack, Clifford R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187496/
https://www.ncbi.nlm.nih.gov/pubmed/28050342
http://dx.doi.org/10.1016/j.nicl.2016.05.017