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Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response

The TAM family of receptors (i.e., Tyro3, Axl, and Mertk), and their ligands Growth arrest specific factor 6 (Gas6) and Protein S (Pros1) contribute to several oncogenic processes, such as cell survival, invasion, migration, chemo-resistance, and metastasis, whereby expression often correlates with...

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Detalles Bibliográficos
Autores principales: Davra, Viralkumar, Kimani, Stanley G., Calianese, David, Birge, Raymond B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187505/
https://www.ncbi.nlm.nih.gov/pubmed/27916840
http://dx.doi.org/10.3390/cancers8120107