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Implications and Assessment of the Elastic Behavior of Lamins in Laminopathies

Lamins are mechanosensitive and elastic components of the nuclear lamina that respond to external mechanical cues by altering gene regulation in a feedback mechanism. Numerous mutations in A-type lamins cause a plethora of diverse diseases collectively termed as laminopathies, the majority of which...

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Detalles Bibliográficos
Autores principales: Dutta, Subarna, Bhattacharyya, Maitree, Sengupta, Kaushik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187521/
https://www.ncbi.nlm.nih.gov/pubmed/27754432
http://dx.doi.org/10.3390/cells5040037