Prelamin A Accumulation Attenuates Rac1 Activity and Increases the Intrinsic Migrational Persistence of Aged Vascular Smooth Muscle Cells

Vascular smooth muscle cell (VSMC) motility is essential during both physiological and pathological vessel remodeling. Although ageing has emerged as a major risk factor in the development of cardiovascular disease, our understanding of the impact of ageing on VSMC motility remains limited. Prelamin...

Descripción completa

Detalles Bibliográficos
Autores principales: Porter, Lauren J., Holt, Mark R., Soong, Daniel, Shanahan, Catherine M., Warren, Derek T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187525/
https://www.ncbi.nlm.nih.gov/pubmed/27854297
http://dx.doi.org/10.3390/cells5040041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187525/
https://www.ncbi.nlm.nih.gov/pubmed/27854297
http://dx.doi.org/10.3390/cells5040041

Ejemplares similares