A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan

In gonadal tissues, the Piwi-interacting (piRNA) pathway preserves genomic integrity by employing 23–29 nucleotide (nt) small RNAs complexed with argonaute proteins to suppress parasitic mobile sequences of DNA called transposable elements (TEs). Although recent evidence suggests that the piRNA path...

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Detalles Bibliográficos
Autores principales: Jones, Brian C., Wood, Jason G., Chang, Chengyi, Tam, Austin D., Franklin, Michael J., Siegel, Emily R., Helfand, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187580/
https://www.ncbi.nlm.nih.gov/pubmed/28000665
http://dx.doi.org/10.1038/ncomms13856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187580/
https://www.ncbi.nlm.nih.gov/pubmed/28000665
http://dx.doi.org/10.1038/ncomms13856

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