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Local synthesis of dynein cofactors matches retrograde transport to acutely changing demands
Cytoplasmic dynein mediates retrograde transport in axons, but it is unknown how its transport characteristics are regulated to meet acutely changing demands. We find that stimulus-induced retrograde transport of different cargos requires the local synthesis of different dynein cofactors. Nerve grow...
Autores principales: | Villarin, Joseph M., McCurdy, Ethan P., Martínez, José C., Hengst, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187584/ https://www.ncbi.nlm.nih.gov/pubmed/28000671 http://dx.doi.org/10.1038/ncomms13865 |
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