The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target

p53 is a sequence-specific short-lived transcription factor expressed at low concentrations in various tissues while it is upregulated in damaged, tumoral or inflamed tissue. In normally proliferating cells, p53 protein levels and function are tightly controlled by main regulators, i.e., MDM2 (mouse...

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Detalles Bibliográficos
Autores principales: Fierabracci, Alessandra, Pellegrino, Marsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187775/
https://www.ncbi.nlm.nih.gov/pubmed/27897991
http://dx.doi.org/10.3390/ijms17121975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187775/
https://www.ncbi.nlm.nih.gov/pubmed/27897991
http://dx.doi.org/10.3390/ijms17121975

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