Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex

TP53 is one of the most frequently-mutated and deleted tumor suppressors in cancer, with a dramatic correlation with dismal prognoses. In addition to genetic inactivation, the p53 protein can be functionally inactivated in cancer, through post-transductional modifications, changes in cellular compar...

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Detalles Bibliográficos
Autores principales: Carrà, Giovanna, Crivellaro, Sabrina, Taulli, Riccardo, Guerrasio, Angelo, Saglio, Giuseppe, Morotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187797/
https://www.ncbi.nlm.nih.gov/pubmed/27916821
http://dx.doi.org/10.3390/ijms17121997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187797/
https://www.ncbi.nlm.nih.gov/pubmed/27916821
http://dx.doi.org/10.3390/ijms17121997

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