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Autoimmune Regulator Expression in DC2.4 Cells Regulates the NF-κB Signaling and Cytokine Expression of the Toll-Like Receptor 3 Pathway

Autoimmune regulator (Aire) mutations result in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED), which manifests as multi-organ autoimmunity and chronic mucocutaneous candidiasis (CMC). Indendritic cells (DCs), pattern recognition receptors (PRR), such as Toll-like receptors...

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Detalles Bibliográficos
Autores principales: Sun, Jitong, Niu, Kunwei, Fu, Haiying, Li, Haijun, Li, Yi, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187802/
https://www.ncbi.nlm.nih.gov/pubmed/27916941
http://dx.doi.org/10.3390/ijms17122002