High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer

Approximately 30% of patients with wild type RAS metastatic colorectal cancer are non-responders to anti-epidermal growth factor receptor monoclonal antibodies (anti-EGFR mAbs), possibly due to undetected tumoral subclones harboring RAS mutations. The aim of this study was to analyze the distributio...

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Detalles Bibliográficos
Autores principales: Jeantet, Marion, Tougeron, David, Tachon, Gaelle, Cortes, Ulrich, Archambaut, Céline, Fromont, Gaelle, Karayan-Tapon, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187815/
https://www.ncbi.nlm.nih.gov/pubmed/27916952
http://dx.doi.org/10.3390/ijms17122015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187815/
https://www.ncbi.nlm.nih.gov/pubmed/27916952
http://dx.doi.org/10.3390/ijms17122015

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