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Somatic Cell Nuclear Transfer Followed by CRIPSR/Cas9 Microinjection Results in Highly Efficient Genome Editing in Cloned Pigs

The domestic pig is an ideal “dual purpose” animal model for agricultural and biomedical research. With the availability of genome editing tools such as clustered regularly interspaced short palindromic repeat (CRISPR) and associated nuclease Cas9 (CRISPR/Cas9), it is now possible to perform site-sp...

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Detalles Bibliográficos
Autores principales: Sheets, Timothy P., Park, Chi-Hun, Park, Ki-Eun, Powell, Anne, Donovan, David M., Telugu, Bhanu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187831/
https://www.ncbi.nlm.nih.gov/pubmed/27918485
http://dx.doi.org/10.3390/ijms17122031