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The Emergence of the Dose–Response Concept in Biology and Medicine
A historical assessment of the origin of the dose–response in modern toxicology and its integration as a central concept in biology and medicine is presented. This article provides an overview of how the threshold, linear and biphasic (i.e., hormetic) dose–response models emerged in the late 19th an...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187834/ https://www.ncbi.nlm.nih.gov/pubmed/27929392 http://dx.doi.org/10.3390/ijms17122034 |