Crystallization of Galectin-8 Linker Reveals Intricate Relationship between the N-terminal Tail and the Linker

Galectin-8 (Gal-8) plays a significant role in normal immunological function as well as in cancer. This lectin contains two carbohydrate recognition domains (CRD) connected by a peptide linker. The N-terminal CRD determines ligand binding specificity, whereas the linker has been proposed to regulate...

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Detalles Bibliográficos
Autores principales: Si, Yunlong, Wang, Yue, Gao, Jin, Song, Chenyang, Feng, Shiqiong, Zhou, Yifa, Tai, Guihua, Su, Jiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187888/
https://www.ncbi.nlm.nih.gov/pubmed/27973456
http://dx.doi.org/10.3390/ijms17122088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187888/
https://www.ncbi.nlm.nih.gov/pubmed/27973456
http://dx.doi.org/10.3390/ijms17122088

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