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Crystallization of Galectin-8 Linker Reveals Intricate Relationship between the N-terminal Tail and the Linker
Galectin-8 (Gal-8) plays a significant role in normal immunological function as well as in cancer. This lectin contains two carbohydrate recognition domains (CRD) connected by a peptide linker. The N-terminal CRD determines ligand binding specificity, whereas the linker has been proposed to regulate...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187888/ https://www.ncbi.nlm.nih.gov/pubmed/27973456 http://dx.doi.org/10.3390/ijms17122088 |