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Effect of the CRAC Peptide, VLNYYVW, on mPTP Opening in Rat Brain and Liver Mitochondria

The translocator protein (TSPO; 18 kDa) is a high-affinity cholesterol-binding protein located in the outer membrane of mitochondria. A domain in the C-terminus of TSPO was characterized as the cholesterol recognition/interaction amino acid consensus (CRAC). The ability of the CRAC domain to bind to...

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Detalles Bibliográficos
Autores principales: Azarashvili, Tamara, Krestinina, Olga, Baburina, Yulia, Odinokova, Irina, Akatov, Vladimir, Beletsky, Igor, Lemasters, John, Papadopoulos, Vassilios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187896/
https://www.ncbi.nlm.nih.gov/pubmed/27983605
http://dx.doi.org/10.3390/ijms17122096