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Discovery of a New Class of Cathepsin K Inhibitors in Rhizoma Drynariae as Potential Candidates for the Treatment of Osteoporosis

Rhizoma Drynariae (RD), as one of the most common clinically used folk medicines, has been reported to exert potent anti-osteoporotic activity. The bioactive ingredients and mechanisms that account for its bone protective effects are under active investigation. Here we adopt a novel in silico target...

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Detalles Bibliográficos
Autores principales: Qiu, Zuo-Cheng, Dong, Xiao-Li, Dai, Yi, Xiao, Gao-Keng, Wang, Xin-Luan, Wong, Ka-Chun, Wong, Man-Sau, Yao, Xin-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187916/
https://www.ncbi.nlm.nih.gov/pubmed/27999266
http://dx.doi.org/10.3390/ijms17122116