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Downregulation of Homer1b/c in SOD1 G93A Models of ALS: A Novel Mechanism of Neuroprotective Effect of Lithium and Valproic Acid

Background: Mutations in the Cu/Zn superoxide dismutase (SOD1) gene have been linked to amyotrophic lateral sclerosis (ALS). However, the molecular mechanisms have not been elucidated yet. Homer family protein Homer1b/c is expressed widely in the central nervous system and plays important roles in n...

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Detalles Bibliográficos
Autores principales: Jiang, Hai-Zhi, Wang, Shu-Yu, Yin, Xiang, Jiang, Hong-Quan, Wang, Xu-Dong, Wang, Jing, Wang, Tian-Hang, Qi, Yan, Yang, Yue-Qing, Wang, Ying, Zhang, Chun-Ting, Feng, Hong-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187929/
https://www.ncbi.nlm.nih.gov/pubmed/27999308
http://dx.doi.org/10.3390/ijms17122129