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EGFR and KRAS Mutations Predict the Incidence and Outcome of Brain Metastases in Non-Small Cell Lung Cancer

Background: Lung cancer is the leading cause of brain metastases (BM). The identification of driver oncogenes and matched targeted therapies has improved outcome in non-small cell lung cancer (NSCLC) patients; however, a better understanding of BM molecular biology is needed to further drive the pro...

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Detalles Bibliográficos
Autores principales: Tomasini, Pascale, Serdjebi, Cindy, Khobta, Nataliya, Metellus, Philippe, Ouafik, L’Houcine, Nanni, Isabelle, Greillier, Laurent, Loundou, Anderson, Fina, Frederic, Mascaux, Celine, Barlesi, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187932/
https://www.ncbi.nlm.nih.gov/pubmed/27999344
http://dx.doi.org/10.3390/ijms17122132