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Neuropeptide Y1 Receptor Regulates Glucocorticoid-Induced Inhibition of Osteoblast Differentiation in Murine MC3T3-E1 Cells via ERK Signaling

High dose glucocorticoid (GC) administration impairs the viability and function of osteoblasts, thus causing osteoporosis and osteonecrosis. Neuropeptide Y1 receptor (Y1 receptor) is expressed in bone tissues and cells, and regulates bone remodeling. However, the role of Y1 receptor in glucocorticoi...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Zhu, Chao, Xu, Wenning, Jiang, Leisheng, Jiang, Shengdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187950/
https://www.ncbi.nlm.nih.gov/pubmed/28009825
http://dx.doi.org/10.3390/ijms17122150