Lithium carbonate and coenzyme Q10 reduce cell death in a cell model of Machado-Joseph disease

Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by expansion of the polyglutamine domain of the ataxin-3 (ATX3) protein. MJD/SCA3 is the most frequent autosomal dominant ataxia in many countries. The mechanism underlying...

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Detalles Bibliográficos
Autores principales: Lopes-Ramos, C.M., Pereira, T.C., Dogini, D.B., Gilioli, R., Lopes-Cendes, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2016
Materias:
Biomedical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5188859/
https://www.ncbi.nlm.nih.gov/pubmed/27878228
http://dx.doi.org/10.1590/1414-431X20165805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5188859/
https://www.ncbi.nlm.nih.gov/pubmed/27878228
http://dx.doi.org/10.1590/1414-431X20165805

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