Sirtuin1 (SIRT1) Regulates Tumor Necrosis Factor-alpha (TNF-α-Induced) Aquaporin-2 (AQP2) Expression in Renal Medullary Collecting Duct Cells Through Inhibiting the NF-κB Pathway

BACKGROUND: Aquaporin-2 (AQP2) plays a major role in water reabsorption in the renal collecting duct, and is involved in a variety of renal disease. Recent studies have indicate that sirtuin1 (SIRT1) exerts renoprotective properties against kidney diseases. This study aimed to determine the potentia...

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Detalles Bibliográficos
Autores principales: Lin, Qinqin, Geng, Yuanwen, Lin, Shuaishuai, Tian, Zhenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189724/
https://www.ncbi.nlm.nih.gov/pubmed/27980322
http://dx.doi.org/10.12659/MSMBR.901909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189724/
https://www.ncbi.nlm.nih.gov/pubmed/27980322
http://dx.doi.org/10.12659/MSMBR.901909

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