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Cell Fate Decision as High-Dimensional Critical State Transition

Cell fate choice and commitment of multipotent progenitor cells to a differentiated lineage requires broad changes of their gene expression profile. But how progenitor cells overcome the stability of their gene expression configuration (attractor) to exit the attractor in one direction remains elusi...

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Detalles Bibliográficos
Autores principales: Mojtahedi, Mitra, Skupin, Alexander, Zhou, Joseph, Castaño, Ivan G., Leong-Quong, Rebecca Y. Y., Chang, Hannah, Trachana, Kalliopi, Giuliani, Alessandro, Huang, Sui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189937/
https://www.ncbi.nlm.nih.gov/pubmed/28027308
http://dx.doi.org/10.1371/journal.pbio.2000640