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Cell Fate Decision as High-Dimensional Critical State Transition
Cell fate choice and commitment of multipotent progenitor cells to a differentiated lineage requires broad changes of their gene expression profile. But how progenitor cells overcome the stability of their gene expression configuration (attractor) to exit the attractor in one direction remains elusi...
Autores principales: | Mojtahedi, Mitra, Skupin, Alexander, Zhou, Joseph, Castaño, Ivan G., Leong-Quong, Rebecca Y. Y., Chang, Hannah, Trachana, Kalliopi, Giuliani, Alessandro, Huang, Sui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189937/ https://www.ncbi.nlm.nih.gov/pubmed/28027308 http://dx.doi.org/10.1371/journal.pbio.2000640 |
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