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Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study

BACKGROUND: Endometrial cancer is the most common gynecologic malignancy, and its incidence and associated mortality are increasing. Despite the immediate need to detect these cancers at an earlier stage, there is no effective screening methodology or protocol for endometrial cancer. The comprehensi...

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Detalles Bibliográficos
Autores principales: Nair, Navya, Camacho-Vanegas, Olga, Rykunov, Dmitry, Dashkoff, Matthew, Camacho, Sandra Catalina, Schumacher, Cassie A., Irish, Jonathan C., Harkins, Timothy T., Freeman, Elijah, Garcia, Isaac, Pereira, Elena, Kendall, Sviatoslav, Belfer, Rachel, Kalir, Tamara, Sebra, Robert, Reva, Boris, Dottino, Peter, Martignetti, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189938/
https://www.ncbi.nlm.nih.gov/pubmed/28027320
http://dx.doi.org/10.1371/journal.pmed.1002206