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Base-Position Error Rate Analysis of Next-Generation Sequencing Applied to Circulating Tumor DNA in Non-Small Cell Lung Cancer: A Prospective Study

BACKGROUND: Circulating tumor DNA (ctDNA) is an approved noninvasive biomarker to test for the presence of EGFR mutations at diagnosis or recurrence of lung cancer. However, studies evaluating ctDNA as a noninvasive “real-time” biomarker to provide prognostic and predictive information in treatment...

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Detalles Bibliográficos
Autores principales: Pécuchet, Nicolas, Zonta, Eleonora, Didelot, Audrey, Combe, Pierre, Thibault, Constance, Gibault, Laure, Lours, Camille, Rozenholc, Yves, Taly, Valérie, Laurent-Puig, Pierre, Blons, Hélène, Fabre, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189949/
https://www.ncbi.nlm.nih.gov/pubmed/28027313
http://dx.doi.org/10.1371/journal.pmed.1002199