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Feedback Loops of the Mammalian Circadian Clock Constitute Repressilator
Mammals evolved an endogenous timing system to coordinate their physiology and behaviour to the 24h period of the solar day. While it is well accepted that circadian rhythms are generated by intracellular transcriptional feedback loops, it is still debated which network motifs are necessary and suff...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189953/ https://www.ncbi.nlm.nih.gov/pubmed/27942033 http://dx.doi.org/10.1371/journal.pcbi.1005266 |